SYK vs VRTX
SYK: A diversified medical technology leader offering surgical equipment, orthopedic robotics, and minimally invasive neurovascular products that collectively serve over 150 million patients annually across 61 countries. VRTX: Vertex Pharmaceuticals develops transformative medicines for serious genetic diseases, with a dominant pipeline anchored in cystic fibrosis treatments and groundbreaking gene-editing therapies for blood disorders and pain.
Side-by-side fundamentals
| Metric | SYK | VRTX | Edge |
|---|---|---|---|
| Price as of 2026-07-09 close | $327.11 | $498.43 | |
| Market cap as of 2026-07-10 | $126.0B | $130.3B | |
| P/E as of 2026-07-10 | 37.74 | 30.05 | VRTX lower |
| PEG as of 2026-07-10 | 3.29 | 2.31 | VRTX lower |
| Net margin as of 2026-07-10 | +13.2% | +35.5% | VRTX higher |
| Gross margin as of 2026-07-10 | +64.2% | +86.2% | VRTX higher |
| Operating margin as of 2026-07-10 | +19.7% | +38.3% | VRTX higher |
| ROE as of 2026-07-10 | +15.1% | +23.9% | VRTX higher |
| ROA as of 2026-07-10 | +7.1% | +17.2% | VRTX higher |
| Debt / equity as of 2026-07-10 | 0.64 | 0.01 | VRTX lower |
| Revenue growth (YoY) as of 2026-07-10 | +8.8% | +10.1% | VRTX higher |
| Revenue CAGR (3y) SEC XBRL | +10.8% | +10.4% | SYK higher |
| Dividend yield as of 2026-07-10 | +1.1% | n/a | |
| Dividend streak (yrs) SEC XBRL | 5 | n/a | |
| Beta as of 2026-07-10 | 0.78 | 0.29 | |
| 1-year return as of 2026-07-09 close | -16.6% | +6.9% | VRTX higher |
Fundamentals: Finnhub, as of 2026-07-10. Filings: SEC EDGAR. Prices are delayed daily-close data.
Last updated 2026-07-09.
Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & Finnhub, shown with their as-of date; "Edge" cells are a pure numeric comparison, not a recommendation.