AGIO vs SEPN
AGIO: A commercial-stage biopharmaceutical company focused on transforming the treatment landscape for rare genetic hematologic diseases through its innovative pyruvate kinase activator technology. SEPN: An early-stage biotech company developing cell receptor-targeted therapeutics for inflammation, metabolism, and other diseases through its proprietary chemistry platform.
Side-by-side fundamentals
| Metric | AGIO | SEPN | Edge |
|---|---|---|---|
| Price as of 2026-07-22 close | $36.05 | $34.20 | |
| Market cap as of 2026-07-23 | $2.2B | $1.5B | |
| Net margin as of 2026-07-23 | -639.8% | -49.9% | SEPN higher |
| Gross margin as of 2026-07-23 | +90.0% | n/a | |
| Operating margin as of 2026-07-23 | -720.0% | -77.1% | SEPN higher |
| ROE as of 2026-07-23 | -34.1% | -9.4% | SEPN higher |
| ROA as of 2026-07-23 | -31.7% | -6.6% | SEPN higher |
| Debt / equity as of 2026-07-23 | 0.00 | 0.00 | Tie |
| Revenue growth (YoY) as of 2026-07-23 | +78.3% | +11790.1% | SEPN higher |
| Revenue CAGR (3y) SEC XBRL | +56.0% | +1644.5% | SEPN higher |
| Beta as of 2026-07-23 | 0.58 | 0.62 | |
| 1-year return as of 2026-07-22 close | -6.4% | +173.6% | SEPN higher |
Fundamentals: Finnhub, as of 2026-07-23. Filings: SEC EDGAR. Prices are delayed daily-close data.
Last updated 2026-07-22.
Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & Finnhub, shown with their as-of date; "Edge" cells are a pure numeric comparison, not a recommendation.