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CLYM vs UPB

CLYM: Clinical-stage biotech developing budoprutug, an anti-CD19 monoclonal antibody for B-cell depletion in autoimmune diseases including membranous nephropathy and lupus. UPB: Upstream Bio is a clinical-stage biotech developing verekitug, a potentially best-in-class monoclonal antibody targeting the TSLP receptor for the treatment of severe respiratory inflammatory diseases.

Side-by-side fundamentals

MetricCLYMUPBEdge
Price as of 2026-07-22 close$12.58$6.59
Market cap as of 2026-07-23$720M$376M
Net margin as of 2026-07-23n/a-4719.0%
Operating margin as of 2026-07-23n/a-5176.5%
ROE as of 2026-07-23-31.5%-43.8%CLYM higher
ROA as of 2026-07-23-30.4%-42.3%CLYM higher
Debt / equity as of 2026-07-230.000.00Tie
Revenue growth (YoY) as of 2026-07-23n/a+13.2%
Revenue CAGR (3y) SEC XBRLn/a+9.5%
Beta as of 2026-07-230.101.77
1-year return as of 2026-07-22 close+829.1%-34.4%CLYM higher

Fundamentals: Finnhub, as of 2026-07-23. Filings: SEC EDGAR. Prices are delayed daily-close data.

Last updated 2026-07-22.

Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & Finnhub, shown with their as-of date; "Edge" cells are a pure numeric comparison, not a recommendation.