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FULC vs SION

FULC: Fulcrum Therapeutics is a clinical-stage biopharmaceutical company focused on unlocking gene expression to treat serious, rare genetic diseases. SION: A clinical-stage biotech pioneering the first drugs to directly stabilize CFTR's NBD1 domain, tackling the "undruggable" target in cystic fibrosis.

Side-by-side fundamentals

MetricFULCSIONEdge
Price as of 2026-07-31 close$3.58$47.13
Market cap as of 2026-08-03$273M$2.1B
PEG as of 2026-08-03n/a-0.89
Net margin as of 2026-08-03+8.1%n/a
Operating margin as of 2026-08-03-3.6%n/a
ROE as of 2026-08-03-22.5%-27.3%FULC higher
ROA as of 2026-08-03-21.2%-25.9%FULC higher
Debt / equity as of 2026-08-030.000.00Tie
Beta as of 2026-08-031.340.91
1-year return as of 2026-07-31 close-46.8%+181.2%SION higher

Fundamentals: market data, as of 2026-08-03. Filings: SEC EDGAR. Prices are delayed daily-close data.

Last updated 2026-07-31.

Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & market data, shown with their as-of date; "Edge" cells are a pure numeric comparison, not a recommendation.