PFE vs PYXS
PFE: Global biopharmaceutical company discovering, developing, and manufacturing prescription medicines and vaccines across oncology, immunology, cardiovascular, and infectious disease. PYXS: Pyxis Oncology is a clinical-stage biopharma developing innovative antibody-drug conjugates (ADCs) that target the tumor microenvironment to improve efficacy in difficult-to-treat solid tumors.
Side-by-side fundamentals
| Metric | PFE | PYXS | Edge |
|---|---|---|---|
| Price as of 2026-07-22 close | $24.82 | $2.53 | |
| Market cap as of 2026-07-23 | $142.0B | $160M | |
| P/E as of 2026-07-23 | 18.96 | n/a | |
| PEG as of 2026-07-23 | -3.38 | n/a | |
| Net margin as of 2026-07-23 | +11.8% | -574.5% | PFE higher |
| Gross margin as of 2026-07-23 | +74.8% | +82.8% | PYXS higher |
| Operating margin as of 2026-07-23 | +15.4% | -609.2% | PFE higher |
| ROE as of 2026-07-23 | +8.4% | -70.8% | PFE higher |
| ROA as of 2026-07-23 | +3.6% | -49.3% | PFE higher |
| Debt / equity as of 2026-07-23 | 0.72 | 0.00 | PYXS lower |
| Revenue growth (YoY) as of 2026-07-23 | +1.4% | -14.2% | PFE higher |
| Revenue CAGR (3y) SEC XBRL | -14.8% | n/a | |
| Dividend yield as of 2026-07-23 | +6.9% | n/a | |
| Dividend streak (yrs) SEC XBRL | 5 | n/a | |
| Beta as of 2026-07-23 | 0.28 | 1.32 | |
| 1-year return as of 2026-07-22 close | -1.3% | +97.3% | PYXS higher |
Fundamentals: Finnhub, as of 2026-07-23. Filings: SEC EDGAR. Prices are delayed daily-close data.
Last updated 2026-07-22.
Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & Finnhub, shown with their as-of date; "Edge" cells are a pure numeric comparison, not a recommendation.