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ESPERION THERAPEUTICS INC (ESPR)

Health Care · NASDAQ

Esperion commercializes NEXLETOL and NEXLIZET, first-in-class non-statin ACLY inhibitors proven to reduce cardiovascular risk in statin-intolerant or statin-unwilling patients with elevated cholesterol.

What ESPERION THERAPEUTICS INC does

Esperion is a commercial-stage biopharmaceutical company that has developed and is commercializing FDA-approved oral, once-daily, non-statin medicines for patients with elevated LDL cholesterol and cardiovascular disease risk. The company's lead products are NEXLETOL (bempedoic acid) and NEXLIZET (bempedoic acid and ezetimibe), which are first-in-class ACLY (ATP Citrate Lyase) inhibitors approved in the U.S., Europe, and other territories. Beyond its approved bempedoic acid franchise, Esperion is advancing a preclinical pipeline of next-generation ACLY inhibitors and pursuing business development to expand its commercial portfolio.

Themes: ["cardiovascular disease / LDL cholesterol management","non-statin therapies","ACLY inhibitors","hyperlipidemia / hypercholesterolemia treatment"]

Fundamentals

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Key risks (from latest filing)

["Commercial execution risk: reliance on successful market penetration of NEXLETOL and NEXLIZET in the U.S. and Europe to drive revenue growth and achieve profitability","Significant debt and royalty obligations: company carries convertible notes, long-term debt, and royalty sale liabilities totaling approximately $441 million, creating ongoing interest expense burden despite recent profitability approach","Competitive and regulatory risk: non-statin cholesterol management faces competition from established therapies (PCSK9 inhibitors, inclisiran) and GLP-1 agonist obesity drugs which may reduce cardiovascular event risk in high-risk patients"]

See ESPR's biggest risks from its latest 10-Q →

Fundamentals: Finnhub, as of 2026-07-10. Filings: SEC EDGAR. Prices are delayed daily-close data.

Last updated 2026-07-09.

Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & Finnhub, shown with their as-of date.