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OPKO HEALTH INC (OPK) — insider trading

Health Care · NASDAQ

OPKO HEALTH INC (OPK) has 31 reported SEC Form 4 insider transactions in our data, including 22 open-market purchases among the most recent 31 (latest 2026-07-24).

Recent Form 4 transactions

DateInsiderRoleTypeSharesPriceValueFiling
2026-07-24 Rubin Steven D Director, Officer (Executive VP-Administration) Shares withheld for taxes / exercise cost 53,266 $1.22 $65.0K Form 4
2026-07-24 Logal Adam Officer (Sr. Vice President, CFO) Shares withheld for taxes / exercise cost 53,266 $1.22 $65.0K Form 4
2026-06-18 Yu Alice Lin-Tsing Director Grant / award / vesting (derivative) 30,000 — $0 Form 4
2026-06-18 UPPALURI SUBBARAO V Director Grant / award / vesting (derivative) 80,000 — $0 Form 4
2026-06-18 PFENNIGER RICHARD C JR Director Grant / award / vesting (derivative) 60,000 — $0 Form 4
2026-06-18 PAGANELLI JOHN A Director Grant / award / vesting (derivative) 30,000 — $0 Form 4
2026-06-18 MEDEL ROGER MD Director Grant / award / vesting (derivative) 30,000 — $0 Form 4
2026-06-18 Lachman Prem A Director Grant / award / vesting (derivative) 30,000 — $0 Form 4
2026-03-20 PAGANELLI JOHN A Director Open-market purchase 10,000 $1.14 $11.3K Form 4
2026-03-18 UPPALURI SUBBARAO V Director Grant / award / vesting (derivative) 50,000 — $0 Form 4
2025-11-21 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 192,870 $1.34 $257.5K Form 4
2025-11-21 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 191,490 $1.33 $254.7K Form 4
2025-11-21 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 89,375 $1.33 $118.4K Form 4
2025-11-21 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 3,894 $1.32 $5.1K Form 4
2025-11-21 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 102,371 $1.30 $133.1K Form 4
2025-11-20 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 13,664 $1.35 $18.4K Form 4
2025-11-20 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 1,757 $1.35 $2.4K Form 4
2025-11-20 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 24,579 $1.34 $32.9K Form 4
2025-11-20 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 161,818 $1.34 $216.0K Form 4
2025-11-20 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 211,948 $1.33 $281.9K Form 4
2025-11-20 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 47,105 $1.33 $62.4K Form 4
2025-11-20 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 119,129 $1.32 $157.3K Form 4
2025-11-19 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 155,496 $1.32 $205.3K Form 4
2025-11-19 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 198,904 $1.32 $261.6K Form 4
2025-11-19 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 66,504 $1.31 $87.1K Form 4
2025-11-19 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 12,993 $1.31 $17.0K Form 4
2025-11-19 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 30,082 $1.30 $39.1K Form 4
2025-11-19 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 21,236 $1.30 $27.5K Form 4
2025-11-19 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 300 $1.29 $387 Form 4
2025-11-19 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 58,160 $1.29 $74.7K Form 4
2025-11-19 FROST PHILLIP MD ET AL; Frost Gamma Investments Trust Director, Officer (CEO & Chairman), 10% owner Open-market purchase 36,325 $1.28 $46.5K Form 4

Ask the chat about OPK's insider activity →

Transaction types are the SEC Form 4 codes: open-market purchases (P) and sales (S) are the only rows that reflect open-market conviction. Awards/vesting (A), option exercises (M/X/C), shares withheld for taxes (F) and gifts (G) are compensation or mechanical, not buying or selling on the open market. Sales may be planned and non-discretionary (e.g. a Rule 10b5-1 plan); open-market buying is not a recommendation to buy. Informational only — not financial advice.

Source: SEC EDGAR Form 3/4/5. See the full company profile: OPKO HEALTH INC (OPK).

Last updated 2026-07-24 (most recent filing date).

Informational only — NOT financial advice. Insider filings are sourced from SEC EDGAR and shown with their reported dates.