PROTAGONIST THERAPEUTICS INC (PTGX) — insider trading
Health Care · NASDAQ
PROTAGONIST THERAPEUTICS INC (PTGX) has 71 reported SEC Form 4 insider transactions in our data, including 22 open-market sales among the most recent 71 (latest 2026-09-30).
Recent Form 4 transactions
| Date | Insider | Role | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|---|
| 2026-09-30 | Ali Asif | Officer (Chief Financial Officer) | Option exercise / conversion (derivative) | 5,312 | — | $0 | Form 4 |
| 2026-09-30 | Ali Asif | Officer (Chief Financial Officer) | Option exercise / conversion (derivative) | 15,650 | — | $0 | Form 4 |
| 2026-09-30 | Ali Asif | Officer (Chief Financial Officer) | Option exercise / conversion (derivative) | 28,438 | — | $0 | Form 4 |
| 2026-09-30 | Ali Asif | Officer (Chief Financial Officer) | Option exercise / conversion (derivative) | 9,229 | — | $0 | Form 4 |
| 2026-09-30 | Ali Asif | Officer (Chief Financial Officer) | Open-market sale | 46,034 | $141.78 | $6.53M | Form 4 |
| 2026-09-30 | Ali Asif | Officer (Chief Financial Officer) | Open-market sale | 12,595 | $141.77 | $1.79M | Form 4 |
| 2026-09-30 | Ali Asif | Officer (Chief Financial Officer) | Option exercise / conversion | 5,312 | $12.17 | $64.6K | Form 4 |
| 2026-09-30 | Ali Asif | Officer (Chief Financial Officer) | Option exercise / conversion | 15,650 | $19.19 | $300.3K | Form 4 |
| 2026-09-30 | Ali Asif | Officer (Chief Financial Officer) | Option exercise / conversion | 28,438 | $23.42 | $666.0K | Form 4 |
| 2026-09-30 | Ali Asif | Officer (Chief Financial Officer) | Option exercise / conversion | 9,229 | $38.98 | $359.7K | Form 4 |
| 2026-09-10 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion (derivative) | 7,278 | — | $0 | Form 4 |
| 2026-09-10 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Open-market sale | 7,278 | $144.10 | $1.05M | Form 4 |
| 2026-09-10 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion | 7,278 | $21.58 | $157.1K | Form 4 |
| 2026-09-09 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion (derivative) | 63,548 | — | $0 | Form 4 |
| 2026-09-09 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Open-market sale | 63,548 | $146.18 | $9.29M | Form 4 |
| 2026-09-09 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion | 63,548 | $21.58 | $1.37M | Form 4 |
| 2026-09-08 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion (derivative) | 54,174 | — | $0 | Form 4 |
| 2026-09-08 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Open-market sale | 54,174 | $145.87 | $7.90M | Form 4 |
| 2026-09-08 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion | 54,174 | $21.58 | $1.17M | Form 4 |
| 2026-09-03 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Bona fide gift | 510 | — | $0 | Form 4 |
| 2026-08-11 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion (derivative) | 34,239 | — | $0 | Form 4 |
| 2026-08-11 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Open-market sale | 34,239 | $148.52 | $5.09M | Form 4 |
| 2026-08-11 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion | 34,239 | $21.58 | $738.9K | Form 4 |
| 2026-08-10 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion (derivative) | 65,761 | — | $0 | Form 4 |
| 2026-08-10 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Open-market sale | 65,761 | $149.11 | $9.81M | Form 4 |
| 2026-08-10 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion | 65,761 | $21.58 | $1.42M | Form 4 |
| 2026-06-23 | Waddill William D. | Director | Option exercise / conversion (derivative) | 9,000 | — | $0 | Form 4 |
| 2026-06-23 | Waddill William D. | Director | Open-market sale | 9,000 | $117.94 | $1.06M | Form 4 |
| 2026-06-23 | Waddill William D. | Director | Option exercise / conversion | 9,000 | $16.54 | $148.9K | Form 4 |
| 2026-06-10 | Waddill William D. | Director | Option exercise / conversion (derivative) | 6,000 | — | $0 | Form 4 |
| 2026-06-10 | Waddill William D. | Director | Option exercise / conversion (derivative) | 3,000 | — | $0 | Form 4 |
| 2026-06-10 | Waddill William D. | Director | Open-market sale | 9,000 | $107.68 | $969.1K | Form 4 |
| 2026-06-10 | Waddill William D. | Director | Option exercise / conversion | 6,000 | $16.54 | $99.2K | Form 4 |
| 2026-06-10 | Waddill William D. | Director | Option exercise / conversion | 3,000 | $11.80 | $35.4K | Form 4 |
| 2026-05-29 | Waddill William D. | Director | Option exercise / conversion (derivative) | 9,000 | — | $0 | Form 4 |
| 2026-05-29 | Waddill William D. | Director | Open-market sale | 9,000 | $99.64 | $896.8K | Form 4 |
| 2026-05-29 | Waddill William D. | Director | Option exercise / conversion | 9,000 | $11.80 | $106.2K | Form 4 |
| 2026-05-12 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion (derivative) | 75,000 | — | $0 | Form 4/A |
| 2026-05-12 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Open-market sale | 75,000 | $100.12 | $7.51M | Form 4/A |
| 2026-05-12 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion | 75,000 | $21.58 | $1.62M | Form 4/A |
| 2026-05-12 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion (derivative) | 75,000 | — | $0 | Form 4 |
| 2026-05-12 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Open-market sale | 75,000 | $100.12 | $7.51M | Form 4 |
| 2026-05-12 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion | 75,000 | $21.58 | $1.62M | Form 4 |
| 2026-05-08 | Giraudo Bryan | Director | Open-market sale | 5,130 | $100.00 | $513.0K | Form 4 |
| 2026-05-08 | Giraudo Bryan | Director | Open-market sale | 6,000 | $100.00 | $600.0K | Form 4 |
| 2026-05-07 | Giraudo Bryan | Director | Option exercise / conversion (derivative) | 12,000 | — | $0 | Form 4 |
| 2026-05-07 | Giraudo Bryan | Director | Option exercise / conversion (derivative) | 24,000 | — | $0 | Form 4 |
| 2026-05-07 | Giraudo Bryan | Director | Open-market sale | 12,000 | $100.07 | $1.20M | Form 4 |
| 2026-05-07 | Giraudo Bryan | Director | Open-market sale | 36,000 | $100.14 | $3.61M | Form 4 |
| 2026-05-07 | Giraudo Bryan | Director | Option exercise / conversion | 12,000 | $6.98 | $83.8K | Form 4 |
| 2026-05-07 | Giraudo Bryan | Director | Option exercise / conversion | 24,000 | $6.45 | $154.8K | Form 4 |
| 2026-04-23 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Bona fide gift | 1,460 | — | $0 | Form 4 |
| 2026-04-20 | Ali Asif | Officer (Chief Financial Officer) | Open-market sale | 1,750 | $105.47 | $184.6K | Form 4 |
| 2026-03-26 | Ali Asif | Officer (Chief Financial Officer) | Option exercise / conversion (derivative) | 5,265 | — | $0 | Form 4 |
| 2026-03-26 | Ali Asif | Officer (Chief Financial Officer) | Option exercise / conversion (derivative) | 19,500 | — | $0 | Form 4 |
| 2026-03-26 | Ali Asif | Officer (Chief Financial Officer) | Open-market sale | 24,765 | $104.24 | $2.58M | Form 4 |
| 2026-03-26 | Ali Asif | Officer (Chief Financial Officer) | Option exercise / conversion | 5,265 | $12.17 | $64.1K | Form 4 |
| 2026-03-26 | Ali Asif | Officer (Chief Financial Officer) | Option exercise / conversion | 19,500 | $19.19 | $374.2K | Form 4 |
| 2026-03-26 | SELICK HAROLD E | Director | Option exercise / conversion (derivative) | 24,000 | — | $0 | Form 4 |
| 2026-03-26 | SELICK HAROLD E | Director | Open-market sale | 24,000 | $105.00 | $2.52M | Form 4 |
| 2026-03-26 | SELICK HAROLD E | Director | Option exercise / conversion | 24,000 | $12.88 | $309.1K | Form 4 |
| 2026-03-26 | MOLINA ARTURO MD | Officer (Chief Medical Officer) | Option exercise / conversion (derivative) | 15,000 | — | $0 | Form 4 |
| 2026-03-26 | MOLINA ARTURO MD | Officer (Chief Medical Officer) | Open-market sale | 15,000 | $104.79 | $1.57M | Form 4 |
| 2026-03-26 | MOLINA ARTURO MD | Officer (Chief Medical Officer) | Option exercise / conversion | 15,000 | $8.04 | $120.6K | Form 4 |
| 2026-03-25 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion (derivative) | 54,641 | — | $0 | Form 4 |
| 2026-03-25 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Open-market sale | 54,641 | $101.00 | $5.52M | Form 4 |
| 2026-03-25 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion | 54,641 | $8.58 | $468.8K | Form 4 |
| 2026-03-24 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion (derivative) | 59 | — | $0 | Form 4 |
| 2026-03-24 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Open-market sale | 59 | $101.00 | $6.0K | Form 4 |
| 2026-03-24 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Option exercise / conversion | 59 | $8.58 | $506 | Form 4 |
| 2026-03-23 | PATEL DINESH V PH D | Director, Officer (President and CEO) | Bona fide gift | 50,000 | — | $0 | Form 4 |
Ask the chat about PTGX's insider activity →
Transaction types are the SEC Form 4 codes: open-market purchases (P) and sales (S) are the only rows that reflect open-market conviction. Awards/vesting (A), option exercises (M/X/C), shares withheld for taxes (F) and gifts (G) are compensation or mechanical, not buying or selling on the open market. Sales may be planned and non-discretionary (e.g. a Rule 10b5-1 plan); open-market buying is not a recommendation to buy. Informational only — not financial advice.
Source: SEC EDGAR Form 3/4/5. See the full company profile: PROTAGONIST THERAPEUTICS INC (PTGX).
Last updated 2026-09-30 (most recent filing date).
Informational only — NOT financial advice. Insider filings are sourced from SEC EDGAR and shown with their reported dates.