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SPYRE THERAPEUTICS INC (SYRE) — large price moves

Health Care · NASDAQ

Single sessions where SYRE closed 10% or more away from the previous close, between 2025-10-08 and 2026-10-08. Each one lists the events filed in the 5 days ending at that session, in date order.

Of the 13 moves listed, 7 have at least one filed event in the 5 days ending at the session, and 6 have none. Across the catalog most large moves have nothing filed near them, so an empty list is an ordinary result and not a gap.

Moves

  • 2026-10-06 -13.6% $92.72 to $80.11 filed events in the 5 days to 2026-10-06
    • 2026-10-01 Insider trade Open-market sale reported by an insider16 transactions · 3 insiders · $4,702,762Source: SEC Form 4
  • 2026-08-26 -12.8% $107.36 to $93.61 filed events in the 5 days to 2026-08-26
    • 2026-08-25 Analyst consensus Consensus price target moved upconsensus target $105.79 to $124.71 · between snapshots 2026-08-01 and 2026-08-25 · 14 analystsSource: Analyst consensus snapshots
  • 2026-08-04 +10.5% $94.93 to $104.94 filed events in the 5 days to 2026-08-04
    • 2026-08-03 Insider trade Open-market sale reported by an insider8 transactions · 2 insiders · $2,149,476Source: SEC Form 4
    • 2026-08-04 Earnings Quarterly results reportedquarter ended 2026-06-30 · reported EPS USD -0.36 against an estimate of USD -0.75 · surprise +51.8%Source: SEC filing calendar + Yahoo earnings history
    • 2026-08-04 Periodic filing 10-Q filedaccession 0001636282-26-000096Source: SEC EDGAR
    • 2026-08-04 Material event 8-K filed (material event)accession 0001636282-26-000098Source: SEC EDGAR
  • 2026-06-24 -11.1% $97.05 to $86.24 filed events in the 5 days to 2026-06-24
    • 2026-06-22 Insider trade Open-market sale reported by an insider1 transaction · 1 insider · $2,000,000Source: SEC Form 4
    • 2026-06-23 Insider trade Open-market sale reported by an insider1 transaction · 1 insider · $399,658,667Source: SEC Form 4
  • 2026-06-22 +13.6% $88.34 to $100.32 filed events in the 5 days to 2026-06-22
    • 2026-06-22 Insider trade Open-market sale reported by an insider1 transaction · 1 insider · $2,000,000Source: SEC Form 4
  • 2026-04-13 +23.4% $51.29 to $63.27 filed events in the 5 days to 2026-04-13
    • 2026-04-13 Earnings Quarterly results reportedquarter ended 2026-03-31 · reported EPS USD -0.74 against an estimate of USD -0.65 · surprise -13.1%Source: SEC filing calendar + Yahoo earnings history
    • 2026-04-13 Material event 8-K filed (material event)accession 0001628280-26-024906Source: SEC EDGAR
  • 2026-03-31 +11.1% $45.42 to $50.44 filed events in the 5 days to 2026-03-31

    No filed event was recorded for this company in the 5 days ending on this session. That is what our sources hold, not a statement about what happened.

  • 2026-03-16 +10.5% $39.89 to $44.07 filed events in the 5 days to 2026-03-16

    No filed event was recorded for this company in the 5 days ending on this session. That is what our sources hold, not a statement about what happened.

  • 2026-02-20 +14.3% $37.81 to $43.21 filed events in the 5 days to 2026-02-20
    • 2026-02-19 Earnings Quarterly results reportedquarter ended 2025-12-31 · reported EPS USD -0.74 against an estimate of USD -0.80 · surprise +7.2%Source: SEC filing calendar + Yahoo earnings history
    • 2026-02-19 Periodic filing 10-K filedaccession 0001636282-26-000020Source: SEC EDGAR
  • 2025-12-03 +13.4% $28.40 to $32.20 filed events in the 5 days to 2025-12-03

    No filed event was recorded for this company in the 5 days ending on this session. That is what our sources hold, not a statement about what happened.

  • 2025-11-24 +11.2% $24.26 to $26.97 filed events in the 5 days to 2025-11-24

    No filed event was recorded for this company in the 5 days ending on this session. That is what our sources hold, not a statement about what happened.

  • 2025-10-14 +11.0% $18.92 to $21.00 filed events in the 5 days to 2025-10-14

    No filed event was recorded for this company in the 5 days ending on this session. That is what our sources hold, not a statement about what happened.

  • 2025-10-09 +19.7% $17.68 to $21.17 filed events in the 5 days to 2025-10-09

    No filed event was recorded for this company in the 5 days ending on this session. That is what our sources hold, not a statement about what happened.

These are events filed near a session, listed by date. They are not ranked, and no connection between an event and a price move is stated or implied.

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See the full company profile: SPYRE THERAPEUTICS INC (SYRE).

Informational only — NOT financial advice. Price moves are computed from stored daily closes; filed events come from their own sources with their own dates.