UPSTREAM BIO INC (UPB) — insider trading
Health Care · NASDAQ
UPSTREAM BIO INC (UPB) has 17 reported SEC Form 4 insider transactions in our data, including 11 open-market sales among the most recent 17 (latest 2026-09-16).
Recent Form 4 transactions
| Date | Insider | Role | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|---|
| 2026-09-16 | Sutherland Everett Rand | Director, Officer (Chief Executive Officer) | Open-market sale | 2,095 | $5.49 | $11.5K | Form 4 |
| 2026-09-16 | Houghton Adam | Officer (Chief Business Officer) | Open-market sale | 700 | $5.49 | $3.8K | Form 4 |
| 2026-09-16 | GRAY MICHAEL | Officer (CFO and COO) | Open-market sale | 853 | $5.49 | $4.7K | Form 4 |
| 2026-09-16 | Deykin Aaron | Officer (Chief Medical Officer) | Open-market sale | 895 | $5.49 | $4.9K | Form 4 |
| 2026-09-16 | Ambrose Allison | Officer (General Counsel) | Open-market sale | 485 | $5.49 | $2.7K | Form 4 |
| 2026-06-16 | Ambrose Allison | Officer (General Counsel) | Open-market sale | 477 | $6.10 | $2.9K | Form 4 |
| 2026-06-16 | Deykin Aaron | Officer (Chief Medical Officer) | Open-market sale | 895 | $6.10 | $5.5K | Form 4 |
| 2026-06-16 | Houghton Adam | Officer (Chief Business Officer) | Open-market sale | 700 | $6.10 | $4.3K | Form 4 |
| 2026-06-16 | Sutherland Everett Rand | Director, Officer (Chief Executive Officer) | Open-market sale | 2,095 | $6.10 | $12.8K | Form 4 |
| 2026-06-16 | GRAY MICHAEL | Officer (CFO and COO) | Open-market sale | 853 | $6.10 | $5.2K | Form 4 |
| 2026-06-09 | Chimovits Erez | Director | Grant / award / vesting (derivative) | 17,096 | — | $0 | Form 4 |
| 2026-06-09 | Ratcliffe Liam | Director | Grant / award / vesting (derivative) | 17,096 | — | $0 | Form 4 |
| 2026-06-09 | Beckman Daniella | Director | Grant / award / vesting (derivative) | 17,096 | — | $0 | Form 4 |
| 2026-06-09 | Fleming Harold Edward | Director | Grant / award / vesting (derivative) | 17,096 | — | $0 | Form 4 |
| 2026-06-09 | Renaud Ronald C JR | Director | Grant / award / vesting (derivative) | 17,096 | — | $0 | Form 4 |
| 2026-06-09 | Ruddy Marcella K. | Director | Grant / award / vesting (derivative) | 17,096 | — | $0 | Form 4 |
| 2026-03-16 | GRAY MICHAEL | Officer (CFO and COO) | Open-market sale | 852 | $9.29 | $7.9K | Form 4 |
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Transaction types are the SEC Form 4 codes: open-market purchases (P) and sales (S) are the only rows that reflect open-market conviction. Awards/vesting (A), option exercises (M/X/C), shares withheld for taxes (F) and gifts (G) are compensation or mechanical, not buying or selling on the open market. Sales may be planned and non-discretionary (e.g. a Rule 10b5-1 plan); open-market buying is not a recommendation to buy. Informational only — not financial advice.
Source: SEC EDGAR Form 3/4/5. See the full company profile: UPSTREAM BIO INC (UPB).
Last updated 2026-09-16 (most recent filing date).
Informational only — NOT financial advice. Insider filings are sourced from SEC EDGAR and shown with their reported dates.