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ABOS vs PRTA

ABOS: Acumen Pharmaceuticals is developing a precision immunotherapy targeting toxic amyloid-beta oligomers to provide a disease-modifying treatment for Alzheimer’s disease. PRTA: Prothena is a clinical-stage biotechnology company developing novel therapies for protein dysregulation diseases like Alzheimer's and Parkinson's through a collaborative, partner-focused model.

Side-by-side fundamentals

MetricABOSPRTAEdge
Price as of 2026-10-08 close$2.10$8.61
Market cap$152M$442M
Net margin FY2025, SEC XBRLn/a-2520.6%
Operating margin FY2025, SEC XBRLn/a-2216.4%
ROE FY2025, SEC XBRL-172.3%-87.0%PRTA higher
ROA FY2025, SEC XBRL-98.8%-74.7%PRTA higher
Debt / equity as of 2026-09-030.350.00PRTA lower
Revenue CAGR (3y) SEC XBRLn/a-43.6%
Dividend streak (yrs) SEC XBRL00Tie
Beta as of 2026-09-031.380.77
1-year return as of 2026-10-08 close+11.7%-16.8%ABOS higher

Fundamentals: SEC XBRL company filings for the figures marked with a fiscal year, and market data, as of 2026-09-03 for the rest. Filings: SEC EDGAR. Prices are delayed daily-close data.

Last updated 2026-10-08.

Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & market data, shown with their as-of date; "Edge" cells are a pure numeric comparison, not a recommendation.