ALNY vs IONS
ALNY: Alnylam is a global leader in RNA interference therapeutics, pioneering a new class of genetic medicines to treat rare and serious diseases. IONS: Pioneer in RNA-targeted antisense medicines with seven commercialized products and expanding late-stage pipeline across rare neurological and cardiometabolic diseases, now executing independent U.S. launches while generating royalty revenue from major pharma partnerships.
Side-by-side fundamentals
| Metric | ALNY | IONS | Edge |
|---|---|---|---|
| Price as of 2026-07-22 close | $266.99 | $54.01 | |
| Market cap as of 2026-07-23 | $36.2B | $8.8B | |
| P/E as of 2026-07-23 | 62.77 | n/a | |
| PEG as of 2026-07-23 | 1.11 | n/a | |
| Net margin as of 2026-07-23 | +13.5% | -30.9% | ALNY higher |
| Gross margin as of 2026-07-23 | +80.8% | +98.3% | IONS higher |
| Operating margin as of 2026-07-23 | +16.6% | -33.3% | ALNY higher |
| ROE as of 2026-07-23 | +98.3% | -58.7% | ALNY higher |
| ROA as of 2026-07-23 | +11.8% | -10.1% | ALNY higher |
| Debt / equity as of 2026-07-23 | 2.52 | 4.76 | ALNY lower |
| Revenue growth (YoY) as of 2026-07-23 | +82.6% | +47.4% | ALNY higher |
| Revenue CAGR (3y) SEC XBRL | +53.0% | +17.1% | ALNY higher |
| Beta as of 2026-07-23 | 0.24 | 0.38 | |
| 1-year return as of 2026-07-22 close | -15.3% | +28.5% | IONS higher |
Fundamentals: Finnhub, as of 2026-07-23. Filings: SEC EDGAR. Prices are delayed daily-close data.
Last updated 2026-07-22.
Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & Finnhub, shown with their as-of date; "Edge" cells are a pure numeric comparison, not a recommendation.