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BCRX vs IONS

BCRX: BioCryst Pharmaceuticals is a biotech company focused on commercializing and developing innovative therapies for hereditary angioedema and other rare diseases using structure-guided drug design. IONS: Pioneer in RNA-targeted antisense medicines with seven commercialized products and expanding late-stage pipeline across rare neurological and cardiometabolic diseases, now executing independent U.S. launches while generating royalty revenue from major pharma partnerships.

Side-by-side fundamentals

MetricBCRXIONSEdge
Price as of 2026-07-22 close$9.51$54.01
Market cap as of 2026-07-23$2.4B$8.8B
P/E as of 2026-07-239.20n/a
PEG as of 2026-07-23-0.01n/a
Net margin as of 2026-07-23-51.7%-30.9%IONS higher
Gross margin as of 2026-07-23+97.8%+98.3%IONS higher
Operating margin as of 2026-07-23-45.1%-33.3%IONS higher
ROE as of 2026-07-23-328.8%-58.7%IONS higher
ROA as of 2026-07-23-97.3%-10.1%IONS higher
Debt / equity as of 2026-07-232.264.76BCRX lower
Revenue growth (YoY) as of 2026-07-23+75.9%+47.4%BCRX higher
Revenue CAGR (3y) SEC XBRL+22.8%+17.1%BCRX higher
Beta as of 2026-07-230.570.38
1-year return as of 2026-07-22 close+9.9%+28.5%IONS higher

Fundamentals: Finnhub, as of 2026-07-23. Filings: SEC EDGAR. Prices are delayed daily-close data.

Last updated 2026-07-22.

Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & Finnhub, shown with their as-of date; "Edge" cells are a pure numeric comparison, not a recommendation.