DSGN vs IONS
DSGN: Design Therapeutics is a biopharmaceutical company pioneering GeneTAC small-molecule therapies to treat the root causes of serious genetic diseases. IONS: Ionis Pharmaceuticals is a pioneer in RNA-targeted therapies, transitioning into a commercial-stage biotech with a pipeline focused on neurology and cardiometabolic diseases.
Side-by-side fundamentals
| Metric | DSGN | IONS | Edge |
|---|---|---|---|
| Price as of 2026-10-21 close | $10.73 | $44.27 | |
| Market cap | $672M | $7.4B | |
| Net margin FY2025, SEC XBRL | n/a | -40.4% | |
| Operating margin FY2025, SEC XBRL | n/a | -40.4% | |
| ROE FY2025, SEC XBRL | -32.8% | -78.0% | DSGN higher |
| ROA FY2025, SEC XBRL | -30.9% | -10.8% | IONS higher |
| Revenue growth (YoY) FY2025, SEC XBRL | n/a | +33.8% | |
| Revenue CAGR (3y) SEC XBRL | n/a | +17.1% | |
| Dividend streak (yrs) SEC XBRL | 0 | 0 | Tie |
| Beta as of 2026-09-03 | 1.19 | 0.71 | |
| 1-year return as of 2026-10-21 close | +90.6% | -38.2% | DSGN higher |
Fundamentals: SEC XBRL company filings for the figures marked with a fiscal year, and market data, as of 2026-09-03 for the rest. Filings: SEC EDGAR. Prices are delayed daily-close data.
Last updated 2026-10-21.
Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & market data, shown with their as-of date; "Edge" cells are a pure numeric comparison, not a recommendation.