INSM vs VRTX
INSM: Insmed is a biopharmaceutical company dedicated to transforming the lives of patients suffering from serious and rare respiratory and inflammatory diseases. VRTX: Vertex is a leader in biotechnology primarily recognized for its dominance in cystic fibrosis therapy and its emerging pipeline of gene-editing treatments and non-opioid pain relief.
Side-by-side fundamentals
| Metric | INSM | VRTX | Edge |
|---|---|---|---|
| Price as of 2026-10-20 close | $95.67 | $514.65 | |
| Market cap as of 2026-07-31 (share count; price 2026-10-20) | $20.9B | $130.4B | |
| P/E as of 2026-10-20 | n/a | 29.97 | |
| Net margin FY2025, SEC XBRL | -210.5% | +32.9% | VRTX higher |
| Operating margin FY2025, SEC XBRL | -205.6% | +34.8% | VRTX higher |
| ROE FY2025, SEC XBRL | -172.8% | +21.2% | VRTX higher |
| ROA FY2025, SEC XBRL | -56.4% | +15.4% | VRTX higher |
| Debt / equity filed borrowings, leases excl., balance sheet 2026-06-30 | 0.72 | n/a | |
| Revenue growth (YoY) FY2025, SEC XBRL | +66.7% | +8.9% | INSM higher |
| Revenue CAGR (3y) SEC XBRL | +35.2% | +10.4% | INSM higher |
| Dividend streak (yrs) SEC XBRL | 0 | 0 | Tie |
| Beta as of 2026-09-02 | 0.70 | 0.46 | |
| 1-year return as of 2026-10-20 close | -43.0% | +22.8% | VRTX higher |
Fundamentals: SEC XBRL company filings for the figures marked with a fiscal year, and market data, as of 2026-09-02 for the rest. Filings: SEC EDGAR. Prices are delayed daily-close data.
Last updated 2026-10-20.
Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & market data, shown with their as-of date; "Edge" cells are a pure numeric comparison, not a recommendation.