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RARE vs SPRB

RARE: Ultragenyx is a biopharmaceutical company dedicated to transforming the lives of patients suffering from rare and ultra-rare genetic diseases through innovative therapeutic development. SPRB: A clinical-stage biopharmaceutical company advancing a breakthrough enzyme replacement therapy for the rare, neurodegenerative condition Sanfilippo Syndrome Type B.

Side-by-side fundamentals

MetricRARESPRBEdge
Price as of 2026-10-08 close$15.29$45.54
Market cap$1.5B$131M
Net margin FY2025, SEC XBRL-85.4%n/a
Operating margin FY2025, SEC XBRL-79.5%n/a
ROE FY2025, SEC XBRLn/a-91.7%
ROA FY2025, SEC XBRL-37.5%-73.5%RARE higher
Debt / equity as of 2026-09-0290.540.19SPRB lower
Revenue growth (YoY) as of 2026-09-02+17.5%n/a
Revenue CAGR (3y) SEC XBRL+22.8%n/a
Dividend streak (yrs) SEC XBRL00Tie
Beta as of 2026-09-020.990.83
1-year return as of 2026-10-08 close-50.5%-71.6%RARE higher

Fundamentals: SEC XBRL company filings for the figures marked with a fiscal year, and market data, as of 2026-09-02 for the rest. Filings: SEC EDGAR. Prices are delayed daily-close data.

Last updated 2026-10-08.

Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & market data, shown with their as-of date; "Edge" cells are a pure numeric comparison, not a recommendation.