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Highest return-on-equity Health Care companies

Health Care-sector companies ranked by trailing return on equity (ROE). Delayed fundamentals from market data, shown with their as-of date.

Ranked by roe, Halozyme (HALO) leads the covered catalog at +649.2%.

#CompanySectorROENet marginMarket cap
1 Halozyme (HALO) Health Care +649.2%+22.7%$12.2B
2 COHERUS ONCOLOGY INC (CHRS) Health Care +275.4%n/a$212M
3 AVEANNA HEALTHCARE HOLDINGS INC (AVAH) Health Care +115.7%+9.2%$2.9B
4 Cencora (COR) Health Care +103.1%+0.5%$63.2B
5 Medpace (MEDP) Health Care +98.3%+17.8%$16.3B
6 RIGEL PHARMACEUTICALS INC (RIGL) Health Care +93.8%+124.7%$887M
7 Amgen (AMGN) Health Care +89.1%+21.0%$236.9B
8 Zoetis (ZTS) Health Care +80.2%+28.2%$31.9B
9 Lilly (Eli) (LLY) Health Care +77.8%+31.7%$1.09T
10 TG THERAPEUTICS INC (TGTX) Health Care +69.0%+72.6%$8.6B
11 Idexx Laboratories (IDXX) Health Care +66.0%+24.6%$42.9B
12 LIFEMD INC (LFMD) Health Care +62.0%+7.4%$149M
13 ZEVRA THERAPEUTICS INC (ZVRA) Health Care +53.8%n/a$716M
14 NOVO NORDISK A S (NVO) Health Care +52.8%+33.1%$206.0B
15 AURINIA PHARMACEUTICALS INC (AUPH) Health Care +49.4%+101.5%$2.1B
16 ABEONA THERAPEUTICS INC (ABEO) Health Care +44.7%+1223.1%$342M
17 CONCENTRA GROUP HOLDINGS PARENT IN (CON) Health Care +41.5%+7.7%$4.3B
18 CORMEDIX INC (CRMD) Health Care +40.2%+52.3%$653M
19 TRANSMEDICS GROUP INC (TMDX) Health Care +40.2%+31.4%$2.9B
20 Alnylam Pharmaceuticals (ALNY) Health Care +39.8%+8.4%$32.9B
21 Bristol Myers Squibb (BMY) Health Care +38.2%+14.6%$136.7B
22 XOMA ROYALTY CORP (XOMA) Health Care +37.8%+60.8%$504M
23 Gilead Sciences (GILD) Health Care +37.6%+28.9%$185.9B
24 Exelixis (EXEL) Health Care +36.2%+33.7%$14.1B
25 THERAVANCE BIOPHARMA INC (TBPH) Health Care +35.7%+98.5%$884M

Find more highest return-on-equity health care companies like these →

Data: SEC EDGAR (filings) + market data (fundamentals, delayed daily-close). Every figure is shown with its as-of date on the company page; a company with no data for this metric is excluded from the ranking, never estimated.

Last updated 2026-09-03 — rankings shift as the underlying data refreshes.

Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & market data, shown with their as-of date.