TVTX vs ZVRA
TVTX: Rare kidney disease specialist with two approved FILSPARI formulations (IgAN, FSGS) and a clinical-stage enzyme therapy poised to become the first disease-modifying treatment for homocystinuria. ZVRA: Zevra brings life-changing therapies to ultra-rare neurodegenerative and metabolic diseases, with FDA-approved MIPLYFFA for Niemann-Pick disease type C now generating revenue and a pipeline of clinical candidates addressing severe unmet needs.
Side-by-side fundamentals
| Metric | TVTX | ZVRA | Edge |
|---|---|---|---|
| Price as of 2026-07-22 close | $56.26 | $12.14 | |
| Market cap as of 2026-07-23 | $5.2B | $762M | |
| P/E as of 2026-07-23 | n/a | 6.13 | |
| PEG as of 2026-07-23 | 1.06 | n/a | |
| Net margin as of 2026-07-23 | -4.0% | +101.6% | ZVRA higher |
| Gross margin as of 2026-07-23 | +98.6% | +97.9% | TVTX higher |
| Operating margin as of 2026-07-23 | -10.6% | -4.4% | ZVRA higher |
| ROE as of 2026-07-23 | -26.8% | +81.3% | ZVRA higher |
| ROA as of 2026-07-23 | -3.8% | +45.6% | ZVRA higher |
| Debt / equity as of 2026-07-23 | 3.16 | 0.00 | ZVRA lower |
| Revenue growth (YoY) as of 2026-07-23 | +96.0% | +201.3% | ZVRA higher |
| Revenue CAGR (3y) SEC XBRL | +64.9% | n/a | |
| Beta as of 2026-07-23 | 1.02 | 0.90 | |
| 1-year return as of 2026-07-22 close | +259.3% | +4.8% | TVTX higher |
Fundamentals: Finnhub, as of 2026-07-23. Filings: SEC EDGAR. Prices are delayed daily-close data.
Last updated 2026-07-22.
Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & Finnhub, shown with their as-of date; "Edge" cells are a pure numeric comparison, not a recommendation.