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TRAVERE THERAPEUTICS INC (TVTX)

Health Care · Rare kidney and metabolic disease therapeutics · NASDAQ

Rare kidney disease specialist with two approved FILSPARI formulations (IgAN, FSGS) and a clinical-stage enzyme therapy poised to become the first disease-modifying treatment for homocystinuria.

What TRAVERE THERAPEUTICS INC does

Travere Therapeutics is a biopharmaceutical company focused on identifying, developing, and commercializing life-changing therapies for rare kidney and metabolic diseases with significant unmet medical needs. The company has commercialized FILSPARI® (sparsentan), a dual endothelin-angiotensin receptor antagonist approved for IgAN and FSGS, and is advancing pegtibatinase, a novel enzyme replacement therapy for homocystinuria. Travere leverages its specialized commercial organization and rare disease expertise to bring novel treatments to patients with limited existing therapeutic options.

Themes: ["rare kidney diseases","rare metabolic diseases","orphan drugs","IgAN treatment","FSGS treatment","homocystinuria"]

Fundamentals

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Key risks (from latest filing)

["Clinical development risk: pegtibatinase is still in pivotal Phase 3 development with manufacturing scale-up challenges that caused voluntary enrollment pause; success is uncertain","Competitive risk: other companies may develop alternative treatments for IgAN, FSGS, or homocystinuria, potentially reducing addressable market and commercial opportunity","Regulatory and reimbursement risk: orphan drug exclusivity provides protection, but actual patient adoption, insurance coverage, and pricing power may be constrained in small rare disease markets"]

See TVTX's biggest risks from its latest 10-Q →

Competitors & peers

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Fundamentals: Finnhub, as of 2026-07-10. Filings: SEC EDGAR. Prices are delayed daily-close data.

Last updated 2026-07-09.

Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & Finnhub, shown with their as-of date.