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Highest return-on-assets companies

Companies ranked by trailing return on assets (ROA) — how efficiently a business turns its asset base into profit. Delayed fundamentals from market data, shown with their as-of date.

Ranked by ROA: companies 2,876–2,900 of 3,067.

#CompanySectorROANet marginMarket cap
2876 Stereotaxis Inc (STXS) Health Care -41.4%-66.8%$109M
2877 Newsmax Inc Class B (NMAX) Communication Services -41.5%-52.6%$948M
2878 Cibus, Inc. (CBUS) Materials -41.7%-3492.3%$90M
2879 Definium Therapeutics Inc (DFTX) Health Care -41.8%n/a$4.5B
2880 Tyra Biosciences Inc (TYRA) Health Care -42.4%n/a$1.3B
2881 Helen of Troy Limited (HELE) Consumer Discretionary -42.5%-50.3%$876M
2882 Trump Media Technology Group Corp (DJT) Communication Services -42.7%-11077.3%$1.1B
2883 Roadzen Inc (RDZN) Information Technology -42.8%-40.9%$100M
2884 REGENXBIO Inc (RGNX) Health Care -42.8%-113.8%$504M
2885 USA Rare Earth Inc Class A (USAR) Materials -42.8%-18110.7%$3.1B
2886 Iovance Biotherapeutics Inc (IOVA) Health Care -42.8%-148.4%$3.7B
2887 Amylyx Pharmaceuticals Inc (AMLX) Health Care -43.5%n/a$3.8B
2888 Vir Biotechnology Inc (VIR) Health Care -43.7%-638.9%$2.1B
2889 Recursion Pharmaceuticals Inc CLAS (RXRX) Health Care -43.7%-863.4%$2.2B
2890 Sagimet Biosciences Inc Series A (SGMT) Health Care -43.8%-1393.8%$612M
2891 Cartesian Therapeutics Inc (RNAC) Health Care -44.0%-32575.5%$230M
2892 ADC Therapeutics SA (ADCT) Health Care -44.1%-175.3%$202M
2893 Inno Holdings Inc. (INHD) Industrials -44.2%-248.7%$7M
2894 Celldex Therapeutics Inc (CLDX) Health Care -44.4%-16748.0%$2.3B
2895 Relay Therapeutics Inc (RLAY) Health Care -44.5%-1800.6%$4.1B
2896 Sidus Space Inc Class A (SIDU) Industrials -44.6%-871.0%$100M
2897 Anavex Life Sciences Corp (AVXL) Health Care -44.7%n/a$107M
2898 Tonix Pharmaceuticals Holding Corp (TNXP) Health Care -44.7%-946.2%$81M
2899 Denali Therapeutics Inc (DNLI) Health Care -44.8%n/a$3.2B
2900 Accendra Health Inc (ACH) Health Care -44.9%-39.8%$16M

Find more highest return-on-assets companies like these →

Data: SEC EDGAR (filings) + market data (fundamentals, delayed daily-close). Every figure is shown with its as-of date on the company page; a company with no data for this metric is excluded from the ranking, never estimated.

Last updated 2026-11-06 — rankings shift as the underlying data refreshes.

Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & market data, shown with their as-of date.