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Highest return-on-assets companies

Companies ranked by trailing return on assets (ROA) — how efficiently a business turns its asset base into profit. Delayed fundamentals from market data, shown with their as-of date.

Ranked by ROA: companies 3,026–3,050 of 3,067.

#CompanySectorROANet marginMarket cap
3026 Opus Genetics Inc (IRD) Health Care -98.7%-349.3%$348M
3027 Acumen Pharmaceuticals Inc (ABOS) Health Care -98.8%n/a$16M
3028 Connect Biopharma Holdings Limited (CNTB) Health Care -98.9%-86687.5%$46M
3029 Cabaletta Bio Inc (CABA) Health Care -101.7%n/a$220M
3030 Korro Bio Inc (KRRO) Health Care -103.3%-1834.5%$202M
3031 Eightco Holdings Inc. (ORBS) Financials -104.7%-794.4%$321M
3032 TechTarget Inc (TTGT) Communication Services -107.6%-207.1%$191M
3033 Eos Energy Enterprises Inc Class A (EOSE) Industrials -109.5%-849.1%$637M
3034 Sutro Biopharma Inc (STRO) Health Care -109.9%-186.5%$160M
3035 Trisalus LF SC CM A (TLSI) Health Care -111.0%-86.9%$200M
3036 Larimar Therapeutics Inc (LRMR) Health Care -113.6%n/a$248M
3037 Fractyl Health, Inc. (GUTS) Health Care -116.1%n/a$12M
3038 Neumora Therapeutics Inc (NMRA) Health Care -124.0%n/a$95M
3039 Achieve Life Sciences Inc (ACHV) Health Care -130.8%n/a$692M
3040 CapsoVision Inc (CV) Health Care -139.4%-186.8%$316M
3041 Lucid Diagnostics Inc (LUCD) Health Care -143.4%-1047.6%$81M
3042 Summit Therapeutics (SMMT) Health Care -143.7%n/a$13.1B
3043 Vor Biopharma Inc (VOR) Health Care -150.0%n/a$1.2B
3044 Elicio Therapeutics Inc (ELTX) Health Care -153.0%-1225.9%$43M
3045 Ocugen Inc (OCGN) Health Care -155.9%-1537.4%$314M
3046 Galectin Therapeutics Inc (GALT) Health Care -157.9%n/a$317M
3047 Precigen Inc (PGEN) Health Care -161.2%-2588.2%$1.6B
3048 Biohaven Ltd (BHVN) Health Care -163.7%n/a$2.2B
3049 Genelux Corp (GNLX) Health Care -168.9%-401812.5%$89M
3050 ALX Oncology Holdings Inc (ALXO) Health Care -172.2%n/a$160M

Find more highest return-on-assets companies like these →

Data: SEC EDGAR (filings) + market data (fundamentals, delayed daily-close). Every figure is shown with its as-of date on the company page; a company with no data for this metric is excluded from the ranking, never estimated.

Last updated 2026-11-06 — rankings shift as the underlying data refreshes.

Informational only — NOT financial advice. All figures are delayed daily-close data from SEC EDGAR & market data, shown with their as-of date.